Mendoza’s international airport, "Gobernador Francisco Gabrielli" (former "El Plumerillo"), is where domestic flights arrive, connecting Mendoza to the rest of the provinces of Argentina, including Buenos Aires which has direct flights from important cities around the world such as New York, Madrid, Miami, London, São Paolo, Paolo, Rio de Janeiro, Los Angeles, Paris, Amsterdam, Sydney, among others. Mendoza’s airport is also a link to the city of Santiago, Chile and, from there, to the rest of the world.
Take National Route 40 towards. Head south up to Tunuyán Department. (100 kms aprox.) Take Route 92 towards the west until you reach a detour located on the main road (the sign is clearly visible) in direction to Manzano Histórico (25 km from Tunuyán). Take Route 94 to the right and continue until you reach Casa de Uco on the left side of the road.
Take Route 89 towards the south until you reach the Manzano Histórico Monument, then take Route 94 to the left (towards the east). Drive along 10 km up to Casa de Uco, which is on the right side of the road.